The defective protein level of myosin light chain phosphatase (MLCP) in the isolated saphenous vein, as a vascular conduit in coronary artery bypass grafting (CABG), harvested from patients with diabetes mellitus (DM)

Article ID	Journal	Published Year	Pages	File Type
10762686	Biochemical and Biophysical Research Communications	2011	5 Pages	PDF

Abstract

âº Effect of DM on vascular reactivity of human saphenous vein was examined. âº The vasoconstrictions to 5-HT were significantly enhanced in the DM. âº The protein level of MLCP was significantly diminished in the DM. âº The ratio of phosphorylated-MLCP to total MLCP was significantly higher in the DM. âº The defective protein level of MLCP is involved in hyperreactivity in the DM.

Keywords

Diabetes mellitus (DM)

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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The defective protein level of myosin light chain phosphatase (MLCP) in the isolated saphenous vein, as a vascular conduit in coronary artery bypass grafting (CABG), harvested from patients with diabetes mellitus (DM)

Authors

Yasuko Matsuo, Masachika Kuwabara, Naoko Tanaka-Totoribe, Tasuku Kanai, Eisaku Nakamura, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto,