Article ID Journal Published Year Pages File Type
10762689 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► This study investigates the role of galectin-3 in leukemia escape of apoptotic stimuli. ► Inducible galectin-3 is required for leukemia cell survival under apoptotic stimuli. ► Stabilizing Bcl-2 family proteins are regulated for anti-apoptotic galectin-3. ► GSK-3β is activated for inducible galectin-3. ► GSK-3β/galectin-3 is important for the escape of leukemia from apoptotic stimuli.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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