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Specific expression of the human voltage-gated proton channel Hv1 in highly metastatic breast cancer cells, promotes tumor progression and metastasis

Article ID Journal Published Year Pages File Type
10762694 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► Hv1 is specifically expressed in highly metastatic human breast tumor tissues. ► Hv1 regulates breast cancer cytosolic pH. ► Hv1 acidifies extracellular milieu. ► Hv1 exacerbates the migratory ability of metastatic cells.
Keywords
HV1Breast cancerMetastasisProgressionVoltage-gated proton channel
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Specific expression of the human voltage-gated proton channel Hv1 in highly metastatic breast cancer cells, promotes tumor progression and metastasis
Authors
Yifan Wang, Shu Jie Li, Juncheng Pan, Yongzhe Che, Jian Yin, Qing Zhao,
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Biochemical and Biophysical Research Communications
Journal: Biochemical and Biophysical Research Communications
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