| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762698 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Genistein (GEN) is a phytoestrogen found in soy products. ⺠GEN demethylated/unsilenced the steroidogenic factor 1 gene in endometrial tissue. ⺠GEN thus altered mRNA expression in uteri of ovariectomized (OVX) mice. ⺠A high-resolution melting assay was used to screen for epigenetic change. ⺠We isolated an endometrial cell clone that was epigenetically modulated by GEN.
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Authors
Hiroshi Matsukura, Ken-ichi Aisaki, Katsuhide Igarashi, Yuko Matsushima, Jun Kanno, Masaaki Muramatsu, Katsuko Sudo, Noriko Sato,