| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762703 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠PARP1 inhibitors cause a cytotoxic effect independent of DNA repair impairment. ⺠PARP1 inhibitors attenuated AKT-FOXO3A signaling by activating PHLPP1. ⺠PHLPP1 regulates the sensitivity of cancer cells to PARP1 inhibitors.
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Authors
Shuai Wang, Huibo Wang, Ben C. Davis, Jiyong Liang, Rutao Cui, Sai-Juan Chen, Zhi-Xiang Xu,