Article ID Journal Published Year Pages File Type
10762704 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► ATF3 decreases PDX-1 expression in pancreatic β cells. ► ATF3 represses promoter activity of mouse PDX-1. ► ATF3 binds to PDX-1 promoter spanning from −759 to −738. ► ATF3 contributes to downregulation of PDX-1 by hyperglycemia and hyperlipidemia.
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Authors
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