Article ID Journal Published Year Pages File Type
10762713 Biochemical and Biophysical Research Communications 2011 4 Pages PDF
Abstract
► Mitochondria, the main source of ROS, may orchestrate apoptosis and autophagy. ► Autophagy, highly regulated by autophagy-related genes, has many links to cancer. ► Mitochondrial ROS are multifaceted signaling molecules in cancer cells. ► Autophagy plays the Janus role for regulating mitochondrial ROS-mediated pathways. ► Targeting autophagy may be a promising avenue for cancer drug discovery.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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