Article ID Journal Published Year Pages File Type
10762745 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► In this study we studied effect of HIV gp120 on CCL5 production in astrocytes. ► Gp120 up-regulated CCL5 production in astrocytes. ► The increased CCL5 production could be partially abrogated by NF-κB specific inhibitor and siRNA. ► Gp120 mediated CCL5 increase could be interpreted only as mediator of inflammation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
HIV-1 envelope protein gp120 up regulates CCL5 production in astrocytes which can be circumvented by inhibitors of NF-κB pathway
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