Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762750 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Number of γH2AX(S139) foci increases upon CPT-11 treatments. ⺠γH2AX(S139) status is altered by androgens in LNCaP cells. ⺠Number of foci also decreases in PC-3 cells by ectopic NKX3.1 expression. ⺠NKX3.1 expression down-regulates DDR mediators, especially pATM(S1981). ⺠NKX3.1 reprograms S phase transition upon DNA damage by increasing Cyclin D1 expression.
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Authors
Burcu Erbaykent-Tepedelen, Besra Ãzmen, Lokman Varisli, Ceren Gonen-Korkmaz, Bilge Debelec-Butuner, Hamid Muhammed Syed, Ozgur Yilmazer-Cakmak, Kemal Sami Korkmaz,