| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762770 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Leptin treatment of neuronal cells reduces Aβ and phospho-tau levels via AMPK and SIRT1. ⺠Metabolic disturbances in neurons could precede pathological changes in AD. ⺠AMPK or SIRT1 could be drug targets for AD.
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Authors
Steven J. Greco, Ashkan Hamzelou, Jane M. Johnston, Mark A. Smith, J. Wesson Ashford, Nikolaos Tezapsidis,