Article ID Journal Published Year Pages File Type
10762782 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► 14-3-3β interacts with ERα and the interaction is Akt-dependent. ► 14-3-3β regulates the transcriptional activity of ERα in a ligand-dependent manner. ► 14-3-3β increases expressions of ERα target genes. ► 14-3-3β increases breast cancer cell proliferation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The role of 14-3-3β in transcriptional activation of estrogen receptor α and its involvement in proliferation of breast cancer cells
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