| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762812 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Hypoxia is a microenvironmental pathologic factor associated with inflammation. ⺠MCP-1 is one of the crucial cytokines in inflammation. ⺠We examine the mechanisms of the repression of MCP-1 expression under hypoxia. ⺠DNA methylation is attributed to IL-1β-induced MCP-1 expression by hypoxia. ⺠DNA methylation is associated with transient transcriptional repression.
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Authors
Yoko Aoi, Ken-ichi Nakahama, Ikuo Morita, Olga Safronova,