| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762847 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠A yeast two-hybrid screen revealed testin bound to the calcium-sensing receptor. ⺠The second zinc finger of LIM domain 1 of testin is critical for interaction. ⺠Testin bound to a region of the receptor tail important for cell signalling. ⺠Testin and receptor interaction was confirmed in mammalian (HEK293) cells. ⺠Overexpression of testin enhanced receptor-mediated Rho signalling in HEK293 cells.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Aaron L. Magno, Evan Ingley, Suzanne J. Brown, Arthur D. Conigrave, Thomas Ratajczak, Bryan K. Ward,