| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762906 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Transcriptional activation of the Tollitip gene is higher in IECs than in monocytes. ⺠Nt -194/-186 region acts as a cis-element and is recognized by Elf-1. ⺠Elf-1 suppresses Tollip gene transcription in monocytes but not in IECs. ⺠O-GlcNAc modification is necessary for nuclear translocation of Elf-1. ⺠O-GlcNAcylation-dependent nuclear translocation of Elf-1 is impaired in IECs.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Yutaka Sugi, Kyoko Takahashi, Kou Nakano, Akira Hosono, Shuichi Kaminogawa,