| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763015 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Isolated ALDHHi PC3 cells preferentially form primitive holoclone-type colonies. ⺠Primitive holoclone colonies are predominantly ALDHLo but contain rare ALDHHi cells. ⺠Holoclone-forming cells are not restricted to the ALDHHi population. ⺠ALDH phenotypic plasticity occurs in PC3 cells (ALDHLo to ALDHHi and vice versa). ⺠ALDHHi cells are observed but very rare in PC3 spheroids grown in stem cell medium.
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Authors
R.E. Doherty, S.L. Haywood-Small, K. Sisley, N.A. Cross,