Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763028 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠We examine in vivo function of AREBP as a regulator of gluconeogenesis. ⺠We created mice which overexpressed AREBP in order to investigate its function. ⺠AREBP strongly repressed gluconeogenesis gene expressions in the presence of AICAR. ⺠AREBP is a key modulator of hepatic glucose production regulated by AMPK in vivo.
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Authors
Tomomi Shirai, Erina Inoue, Yoshiko Ishimi, Jun Yamauchi,