Article ID Journal Published Year Pages File Type
10763039 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► Oct3/4-positive cells increase in Schistosoma haematobium (SH)-associated bladder cancer. ► iNOS-dependent DNA lesion, 8-nitroguanine, was formed in Oct3/4-positive cells. ► 8-Nitroguanine formed in stem-like cells plays a role in SH-induced carcinogenesis. ► Mutant stem cells may participate in inflammation-related carcinogenesis.
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