Article ID Journal Published Year Pages File Type
10763046 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► NDUFB6 is required for activity of mitochondrial complex I in human cell lines. ► Lentivirus based RNA interference results in frequent off target insertions. ► Flp-In recombinase mediated miRNA insertion allows gene-specific extinction.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The NDUFB6 subunit of the mitochondrial respiratory chain complex I is required for electron transfer activity: A proof of principle study on stable and controlled RNA interference in human cell lines
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