| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763101 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Galectin-9 protein was significantly detected in eosinophil-rich nasal polyps. ⺠Expression of galectin-9 was correlated with the infiltration of eosinophils. ⺠IFN-γ up-regulated galectin-9 expression in human nasal polyp fibroblasts. ⺠The p38 MAPK, SAPK/JNK, PI3K, and JAK pathways are important in the IFN-γ-mediated chemotaxis of galectin-9. ⺠Galectin-9 on the surface of nasal polyp fibroblasts mediated eosinophil adhesion to the cells.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Won Sun Park, Won-Kyo Jung, Seong Kook Park, Kyung Wook Heo, Mi-Seon Kang, Yung Hyun Choi, Gi-Young Kim, Sae-Gwang Park, Su-Kil Seo, Sung Su Yea, Kwang-Hyeon Liu, Eun Bo Shim, Dae-Joong Kim, Minyoung Her, Il-Whan Choi,