| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763105 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Many biological processes have revealed dysregulation of many miRNAs in human diseases. ⺠To better understand collaborative miRNA interactions, we developed a simple platform to express several miRNAs from a single transcript using endogenous pre-miRNA sequences. ⺠This platform will be invaluable as a tool to study the complex and synergistic interactions of aberrantly expressed miRNAs in human diseases and their potential applications in gene therapy.
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Authors
Xiangning Qiu, Jeffrey M. Friedman, Gangning Liang,