Article ID Journal Published Year Pages File Type
10763126 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► Deoxyelephantopin (ESD) inhibited cell proliferation in the human nasopharyngeal cancer CNE cells. ► ESD induced cell cycle arrest in S and G2/M phases via modulation of cell cycle regulatory proteins. ► ESD triggered apoptosis by dysfunction of mitochondria and induction of both intrinsic and extrinsic apoptotic signaling pathways. ► ESD also triggered Akt, ERK, and JNK signaling pathways.
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