Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763126 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Deoxyelephantopin (ESD) inhibited cell proliferation in the human nasopharyngeal cancer CNE cells. ⺠ESD induced cell cycle arrest in S and G2/M phases via modulation of cell cycle regulatory proteins. ⺠ESD triggered apoptosis by dysfunction of mitochondria and induction of both intrinsic and extrinsic apoptotic signaling pathways. ⺠ESD also triggered Akt, ERK, and JNK signaling pathways.
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Authors
Miaoxian Su, Hau Yin Chung, Yaolan Li,