Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763129 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠The expression of phage-displayed disulfide-stabilized sc-dsFv libraries can be drastically enabled with novel signal sequences. ⺠The effective signal sequence variants in the h-region are not necessarily composed of consecutive hydrophobic residues. ⺠Synthetic sc-dsFv library complexities are comparable with the scFv-based libraries. ⺠The disulfide-stabilized sc-dsFv format is a viable alternative for scFv-based applications.
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Authors
Yu-Ching Lee, Ing-Chien Chen, Chung-Ming Yu, Yi-Jen Huang, Hung-Ju Hsu, An-Suei Yang,