| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763131 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Recombinant PEP-1 heme oxygenase-1 expression vector was constructed and overexpressed. ⺠We investigated transduction efficiency of PEP-1-HO-1 protein in Raw 264.7 cells. ⺠PEP-1-HO-1 was efficiently transduced into Raw 264.7 cells in a dose and time dependent manner. ⺠PEP-1-HO-1 exerted anti-inflammatory activity in Raw 264.7 cells and in a mice edema model. ⺠PEP-1-HO-1 could be used as a therapeutic drug against inflammatory diseases.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Soon Won Kwon, Eun Jeong Sohn, Dae Won Kim, Hoon Jae Jeong, Mi Jin Kim, Eun Hee Ahn, Young Nam Kim, Suman Dutta, Duk-Soo Kim, Jinseu Park, Won Sik Eum, Hyun Sook Hwang, Soo Young Choi,