| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763137 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠We examined if N-terminal domain of α-dystroglycan (α-DG-N) is secreted in cerebrospinal fluid. ⺠We generated a new monoclonal antibody against the N-terminal domain of α-DG-N. ⺠A considerable amount of α-DG-N is present in human cerebrospinal fluid. ⺠α-DG-N in cerebrospinal fluid is a sialylated glycoprotein with N- and O-linked glycan. ⺠α-DG-N in cerebrospinal fluid may have unidentified effects on the nervous system.
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Authors
Fumiaki Saito, Yuko Saito-Arai, Ayami Nakamura-Okuma, Miki Ikeda, Hiroki Hagiwara, Toshihiro Masaki, Teruo Shimizu, Kiichiro Matsumura,