Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763243 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Longistatin is less susceptible to SDS-treated platelet lysate. ⺠Longistatin retained 76.73% activity after 3 h of incubation with 20 nM of PAI-1. ⺠Longistatin lysed fibrin clot by activating plasminogen in the presence of PAI-1. ⺠Unlike t-PA, longistatin did not form complex with PAI-1. ⺠Longistatin is a PAI-1 resistant plasminogen activator.
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Authors
Anisuzzaman Anisuzzaman, M. Khyrul Islam, M. Abdul Alim, Takeharu Miyoshi, Takeshi Hatta, Kayoko Yamaji, Yasunobu Matsumoto, Kozo Fujisaki, Naotoshi Tsuji,