Article ID Journal Published Year Pages File Type
10763243 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► Longistatin is less susceptible to SDS-treated platelet lysate. ► Longistatin retained 76.73% activity after 3 h of incubation with 20 nM of PAI-1. ► Longistatin lysed fibrin clot by activating plasminogen in the presence of PAI-1. ► Unlike t-PA, longistatin did not form complex with PAI-1. ► Longistatin is a PAI-1 resistant plasminogen activator.
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