Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763270 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠We show here that ALCL lymphoma cell lines present high levels of Cot (MAP3K8). ⺠We show that Cot mediates the constitutive Erk1/2 activation in SUDHL-1 cells. ⺠Inhibition of Cot activity reduces the number of cell divisions in SUDHL-1 cells. ⺠Cot controls the activation state of p70 S6K and JunB expression in SUDHL-1 cells.
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Authors
Margarita Fernández, Rebeca Manso, Flavia Bernáldez, Pilar López, Antonio MartÃn-Duce, Susana Alemany,