| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763271 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Gossypol is a well known polyphenolic compound used for anticancer studies but we are the first to report that gossypol has antitumor effect on MNNG induced gastric cancer in experimental animal models. ⺠Our study shows that gossypol inhibits the proliferation of AGS (human gastric adenocarcinoma) cell line. ⺠In animal models, gossypol extends the survival of cancer bearing animals and also protects the cells from carcinogenic effect. ⺠So we suggest that gossypol would be a potential chemotherapeutic and chemopreventive agent for gastric cancer.
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Authors
G.R. Gunassekaran, D. Kalpana Deepa Priya, R. Gayathri, D. Sakthisekaran,