Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763274 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠H3K9-K14 acetylation is higher in thyroid tumors than in normal thyroid tissue. ⺠H4K12 acetylation is higher in thyroid adenoma than in thyroid carcinoma. ⺠Oncoproteins RET-PTC, RAS and BRAF increase levels of H3K9-K14 and H3K18 acetylation. ⺠In the rat thyroid cell line FRTL-5, TSH controls levels of histone acetylation.
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Authors
Cinzia Puppin, Nadia Passon, Elisa Lavarone, Carla Di Loreto, Francesco Frasca, Veronica Vella, Riccardo Vigneri, Giuseppe Damante,