Article ID Journal Published Year Pages File Type
10763274 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► H3K9-K14 acetylation is higher in thyroid tumors than in normal thyroid tissue. ► H4K12 acetylation is higher in thyroid adenoma than in thyroid carcinoma. ► Oncoproteins RET-PTC, RAS and BRAF increase levels of H3K9-K14 and H3K18 acetylation. ► In the rat thyroid cell line FRTL-5, TSH controls levels of histone acetylation.
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