Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763286 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠The SAP-like domain in NuSAP is a functional DNA-binding domain with preference for dsDNA. ⺠This SAP-like domain is essential for chromosome loading during early mitosis. ⺠NuSAP is highly dynamic on mitotic chromatin, as evident from photobleaching experiments. ⺠The SAP-like domain also mediates NuSAP-chromatin interaction in interphase nucleoplasm.
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Authors
Werner Verbakel, Geert Carmeliet, Yves Engelborghs,