Article ID Journal Published Year Pages File Type
10763286 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► The SAP-like domain in NuSAP is a functional DNA-binding domain with preference for dsDNA. ► This SAP-like domain is essential for chromosome loading during early mitosis. ► NuSAP is highly dynamic on mitotic chromatin, as evident from photobleaching experiments. ► The SAP-like domain also mediates NuSAP-chromatin interaction in interphase nucleoplasm.
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