| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763308 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠MiR-205 was markedly down-regulated in erbB2-transformed breast epithelial cells. ⺠Restoring miR-205 expression reduced colony formation of the erbB2-transformed cells. ⺠In these cells, cyclin E was shown to be negatively correlated with miR-205 levels. ⺠This work provides a rationale for miR-205 as a novel therapeutic target for erbB2-positive breast cancers.
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Authors
Ryohei Adachi, Shota Horiuchi, Yoshiyuki Sakurazawa, Takuya Hasegawa, Koji Sato, Toshiyuki Sakamaki,