Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763320 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠PAX3 retains embryonic roles in adult melanocytes and melanoma cells. ⺠Promotes “stem” cell-like phenotype via NES and SOX9 in both cells types. ⺠Regulates melanoma and melanocyte migration through MCAM and CSPG4. ⺠PAX3 regulates melanoma but not melanocyte proliferation via TPD52. ⺠Regulates melanoma cell (but not melanocyte) survival via BCL2L1 and PTEN.
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Authors
Sandra Medic, Helen Rizos, Mel Ziman,