Article ID Journal Published Year Pages File Type
10763320 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► PAX3 retains embryonic roles in adult melanocytes and melanoma cells. ► Promotes “stem” cell-like phenotype via NES and SOX9 in both cells types. ► Regulates melanoma and melanocyte migration through MCAM and CSPG4. ► PAX3 regulates melanoma but not melanocyte proliferation via TPD52. ► Regulates melanoma cell (but not melanocyte) survival via BCL2L1 and PTEN.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , ,