| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763326 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠5-Bromodeoxyuridine (BrdU) modulates various biological phenomena such as cellular differentiation and cellular senescence. ⺠To study the molecular mechanism for the action of BrdU, we screened multi-copy suppressor genes that confer resistance to BrdU in Saccharomycescerevisiae. ⺠Expression of N-terminal short fragment of TUP1 and disruption of histone deacetylases that interact with TUP1 conferred resistance to BrdU.
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Authors
Shinichi Takayama, Michihiko Fujii, Yu Nakagawa, Kensuke Miki, Dai Ayusawa,