Article ID Journal Published Year Pages File Type
10763328 Biochemical and Biophysical Research Communications 2011 4 Pages PDF
Abstract
► The singular presence of 5hmC in DNA inhibits transcription. ► Transcription is only inhibited by 5hmC when present at the promoter. ► The presence of 5hmC in the gene body has little effect on transcription.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
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