| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763367 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Nell-1 is a potent pro-osteogenic molecule, but has not yet been studied systematically in adipogenic differentiation. ⺠Using 3T3-L1 cells and primary human ASCs, we found that Nell-1 signaling negatively regulates adipogenic differentiation. ⺠Nell-1 mediated reductions in adipogenesis are associated with increased Hedgehog signaling, which may be a causative factor.
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Authors
Aaron W. James, Angel Pan, Michael Chiang, Janette N. Zara, Xinli Zhang, Kang Ting, Chia Soo,