Article ID Journal Published Year Pages File Type
10763382 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► Hydrogen inhibits LPS/IFNγ-induced NO release through suppressing iNOS expression. ► Hydrogen inhibits LPS/IFNγ-induced activation of ASK1 and its downstream signaling. ► Hydrogen does not affect LPS/IFNγ-induced NOX activation and ROS production. ► Hydrogen alleviates anti-type II collagen antibody-induced arthritis in mice. ► We provide the molecular basis for hydrogen effects on inflammation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages
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