| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763410 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Amlodipine antioxidant and antiinflammatory ability to repair endothelial dysfunction. ⺠Reduced p22phox, NOX4, iNOS expression, NADPHox activity, 4-HNE and 3-nitrotyrosine. ⺠Reduced MCP-1 and VCAM-1 expression and number of monocytes adhered to endothelium. ⺠Decreased phosphorylation of p38 MAPK and p65 NF-κB subunit. ⺠Amlodipine may improve endothelial dysfunction in diabetes.
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Authors
Laura Toma, Camelia S. Stancu, Gabriela M. Sanda, Anca V. Sima,