Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763438 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠The cytoskeleton-associated protein, smALP, is expressed in differentiated skeletal muscle. ⺠smALP is translocated from the cytoplasm to the nucleus of C2C12 myoblasts upon induction of myogenesis. ⺠The differentiation-dependent nuclear translocation of smALP occurs in parallel with the nuclear accumulation of myogenin. ⺠The LIM domain of smALP is essential for the nuclear accumulation of the protein. ⺠smALP might act in the nucleus to control some critical aspect of the muscle differentiation process.
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Authors
Linda Cambier, Pascal Pomiès,