Article ID Journal Published Year Pages File Type
10763438 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► The cytoskeleton-associated protein, smALP, is expressed in differentiated skeletal muscle. ► smALP is translocated from the cytoplasm to the nucleus of C2C12 myoblasts upon induction of myogenesis. ► The differentiation-dependent nuclear translocation of smALP occurs in parallel with the nuclear accumulation of myogenin. ► The LIM domain of smALP is essential for the nuclear accumulation of the protein. ► smALP might act in the nucleus to control some critical aspect of the muscle differentiation process.
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