| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763447 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Soluble FGFR4 extracellular domain (FGFR4-ECD) was effectively expressed. ⺠FGFR4-ECD inhibited FGF19-induced activation of FGFR4 signaling. ⺠FGFR4-ECD reduced palmitic acid-induced steatosis of HepG2 cells. ⺠FGFR4-ECD reduced tetracycline-induced fatty liver in mice. ⺠FGFR4-ECD partially restored tetracycline-repressed PPARα expression.
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Authors
Qiang Chen, Yuan Jiang, Yuan An, Na Zhao, Yang Zhao, Chundong Yu,