| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763465 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Akt interacts with Dlx5 endogenously. ⺠Over-expressed Akt1 induces the phosphorylation of Akt target phosphorylation site(s) and increases the protein level of endogenous Dlx5. Akt1 directly phosphorylates Dlx5 in an in vitro kinase assay. ⺠Wild type Akt1, but not the kinase-defective Akt1, prolongs the half-life of Dlx5. ⺠Akt1 enhances the transcriptional activity of Dlx5 in an Akt kinase activity-dependent manner.
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Authors
Hyung Min Jeong, Yun-Hye Jin, Yeon-Jin Kim, Jinah Yum, You Hee Choi, Chang-Yeol Yeo, Kwang-Youl Lee,