Article ID Journal Published Year Pages File Type
10763470 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► Expression and phosphorylation of CPEB1 is increased by LPS stimulation in rat primary astrocytes. ► JNK regulates expression and phosphorylation of CPEB1 in reactive astrocytes. ► Down-regulation of CPEB1 using siRNA inhibits oxidative stress and iNOS induction by LPS stimulation. ► CPEB1 may play an important role in regulating inflammatory responses in reactive astrocytes induced by LPS.
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