Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763470 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Expression and phosphorylation of CPEB1 is increased by LPS stimulation in rat primary astrocytes. ⺠JNK regulates expression and phosphorylation of CPEB1 in reactive astrocytes. ⺠Down-regulation of CPEB1 using siRNA inhibits oxidative stress and iNOS induction by LPS stimulation. ⺠CPEB1 may play an important role in regulating inflammatory responses in reactive astrocytes induced by LPS.
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Authors
Ki Chan Kim, So Hyun Joo, Chan Young Shin,