Article ID Journal Published Year Pages File Type
10763488 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► 7βOH or 7keto induces early lipid accumulation and lysosomal membrane permeabilization. ► 7βOH or 7keto induces secretion of lysosomal cathepsin D, and up-regulation and release of VWF. ► Oxidative stress and cytosolic release of cytochrome c are involved in apoptosis of endothelial cells caused by 7βOH or 7keto.
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