Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763488 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠7βOH or 7keto induces early lipid accumulation and lysosomal membrane permeabilization. ⺠7βOH or 7keto induces secretion of lysosomal cathepsin D, and up-regulation and release of VWF. ⺠Oxidative stress and cytosolic release of cytochrome c are involved in apoptosis of endothelial cells caused by 7βOH or 7keto.
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Authors
Wei Li, Moumita Ghosh, Sina Eftekhari, Xi-Ming Yuan,