Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763552 | Biochemical and Biophysical Research Communications | 2011 | 4 Pages |
Abstract
⺠Sodium phosphate buffer accelerated Aβ(1-40) nucleation relative to HEPES. ⺠Aβ(1-40) fibrils formed in the two buffers show only minor structural differences. ⺠NMR revealed that Aβ(1-40) histidine residues mediate buffer dependent changes.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Megan Garvey, Katharina Tepper, Caroline Haupt, Uwe Knüpfer, Karolin Klement, Jessica Meinhardt, Uwe Horn, Jochen Balbach, Marcus Fändrich,