| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763568 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠The role of the selectin binding determinant sLex was studied in mo-DCs. ⺠sLex is required for maximal mo-DC binding to endothelial cells. ⺠Mo-DCs bind to selectins via a sLex-dependent pathway. ⺠PSGL-1 is indispensable for P- and L-, but not E-selectin recognition. ⺠IFN-γ increases sLex expression in mo-DCs, probably by enhancing C2GnT-I synthesis.
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Authors
Zélia Silva, ZiQiu Tong, M. Guadalupe Cabral, Catarina Martins, Rita Castro, Celso Reis, Hélder Trindade, Konstantinos Konstantopoulos, Paula A. Videira,