Article ID Journal Published Year Pages File Type
10763577 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► Chronic angiotensin II exerts a stimulatory effect on NHE3 activity and expression. ► Increase in NHE3 mRNA levels is not related with change in NHE3 mRNA stability. ► The stimulatory effect on NHE3 promoter activity involves Sp1/Egr-1 binding site. ► NHE3 promoter stimulation depends on the activation of several intracellular pathways.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Transcriptional regulation of the Na+/H+ exchanger NHE3 by chronic exposure to angiotensin II in renal epithelial cells
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