Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763584 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Metformin inhibited UPR-related marker expression induced by glucosamine (GlcN) and 2-deoxyglucose (2-DOG) in renal epithelial LLC-PK1 cells. ⺠The effect of metformin on UPR-related marker expression inhibition was AMPK-independent. ⺠UPR-related marker expression inhibition mediated by metformin only occurred when LLC-PK1 were cultured in low level of glucose.
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Authors
Jimmy R. Thériault, Helen J. Palmer, Debra D. Pittman,