| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763588 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠In this study we examine miR-34c-3p and miR-34c-5p functions in SiHa cells. ⺠We study miRNA effect on cell proliferation, anchorage independent growth, apoptosis, cell motility and invasion. ⺠We find that miR-34c-3p and miR-34c-5p inhibition of proliferation and anchorage independent growth are exclusive to SiHa cells. ⺠miR-34c-3p induces apoptosis and inhibits cell motility and invasion in SiHa cells. ⺠In this study we conclude that miR-34c-3p functions as a tumor suppressor differ from miR-34c-5p.
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Authors
Jesús Adrián López, Luis Marat Alvarez-Salas,