| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763597 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠It has been suggested that the transcriptional co-regulator Ski plays a role during mitosis. At this stage, Ski is phosphorylated. ⺠Here, we show that Aurora A kinase is able to phosphorylate Ski in vitro. ⺠Immunofluorescence, co-immunoprecipitation and in vitro kinase assays showed that Aurora A-Ski interaction takes place at the centrosomes. ⺠These data identify Ski as a novel target of Aurora A and contribute to understand the role of these proteins in the mitotic process.
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Authors
Jocelyn Mosquera, Ricardo Armisen, Hongling Zhao, Diego A. Rojas, Edio Maldonado, Julio C. Tapia, Alicia Colombo, Michael J. Hayman, Katherine Marcelain,