Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763599 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠RA inhibited BMP4 induction of C3H10T1/2 MSC adipogenic commitment and differentiation. ⺠Adipogenesis inhibition was achieved by adding RA before adipogenic inducers were given. ⺠Among retinoic acid receptors, RARβ was upregulated in RA-treated C3H10T1/2 MSCs. ⺠As a mechanism, BMP4-induced Smad1/5/8 and p38 phosphorylation was suppressed by RA.
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Authors
Jeong Soon Lee, Jin-Hee Park, Il Keun Kwon, Jung Yul Lim,