Article ID Journal Published Year Pages File Type
10763599 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► RA inhibited BMP4 induction of C3H10T1/2 MSC adipogenic commitment and differentiation. ► Adipogenesis inhibition was achieved by adding RA before adipogenic inducers were given. ► Among retinoic acid receptors, RARβ was upregulated in RA-treated C3H10T1/2 MSCs. ► As a mechanism, BMP4-induced Smad1/5/8 and p38 phosphorylation was suppressed by RA.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , ,