| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763615 | Biochemical and Biophysical Research Communications | 2011 | 8 Pages |
Abstract
⺠We performed more detailed analysis of CD9 function for CSC properties in B-ALL. ⺠Leukemogenic fusion/Src family proteins were markedly regulated in the CD9+ cells. ⺠Proliferation of B-ALL cells was inhibited by anti-CD9 monoclonal antibody. ⺠Knockdown of CD9 by RNAi remarkably reduced the leukemogenic potential. ⺠CD9-knockdown affected the expression and phosphorylation of Src family and USP22.
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Authors
Hiroto Yamazaki, C. Wilson Xu, Motohiko Naito, Hiroko Nishida, Toshihiro Okamoto, Farhana Ishrat Ghani, Satoshi Iwata, Takeshi Inukai, Kanji Sugita, Chikao Morimoto,