Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763632 | Biochemical and Biophysical Research Communications | 2011 | 8 Pages |
Abstract
⺠Xanthohumol stimulates osteoblast differentiation by RUNX2 activation. ⺠The mechanisms of osteoblast differentiation by xanthohumol were studied. ⺠Xanthohumol could increase ALP activity and the expression of osteogenic marker genes mediated through RUNX2 activation. ⺠Xanthohumol could up-regulate RUNX2 activation via the p38 MAPK and ERK signaling pathway.
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Authors
Hyung Min Jeong, Eun Hee Han, Yun Hye Jin, You Hee Choi, Kwang Youl Lee, Hye Gwang Jeong,